Sometimes the medication is switched. Commonly people have some additional medication prescribed, called breakthrough medication.
Morphine is the most commonly known pain medication. Hydromorphone is more potent than morphine, which simply means that a smaller quantity of hydromorphone has the same pain relieving effect as a larger quantity of morphine.
For example, someone taking 10 mg of morphine may be switched to 1 or 2 mg of hydromorphone. The degree of pain relief is the same. Both morphine and hydromorphone are used to treat moderate to severe pain. Morphine is often the first medication used. For some patients, however, hydromorphone may be a better first choice. If you have certain health issues, they may change how hydromorphone and morphine work in your body.
It may not be safe for you to take these drugs, or your healthcare provider may need to monitor you more closely during your treatment. You should talk to your healthcare provider before taking hydromorphone or morphine if you have breathing problems such as chronic obstructive pulmonary disease COPD or asthma. These drugs have been linked with serious breathing problems that can cause death. You should also talk about your safety if you have a history of drug abuse or addiction.
These drugs can be addictive and increase your risk of overdose and death. Examples of other medical conditions you should discuss with your healthcare provider before taking hydromorphone or morphine include:. Also, if you have an abnormal heart rhythm , talk to your healthcare provider before using morphine.
It may make your condition worse. Dilaudid and oxycodone are prescription opioids, a class of strong pain-relieving drugs. See how the two compare in side effects, warnings, and more.
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Both drugs also have extended-release forms. This form is given to people who have taken opioids for a long time and need a higher, controlled dose of the drug to be comfortable. Dilaudid and other versions of hydromorphone are stronger drugs than oxycodone. These drugs are often used for serious pain caused by surgery, broken bones , or cancer. The first step is non-opioid analgesic medications.
These drugs are available without a prescription, and include aspirin , ibuprofen , and acetaminophen Tylenol. The third step is potent opioids such as oxycodone and hydromorphone. WHO also recommends scheduled dosing, instead of giving the drugs only as needed, for serious pain. Oxycodone dosing depends on the needs of the patient, as well as whether the drug is in liquid form or as a tablet designed for immediate or extended release.
The dose of hydromorphone also depends on its form, too. The immediate-release forms are usually dosed every four to six hours. The strength of oxycodone or hydromorphone can be gradually increased if a person develops a tolerance for the drugs or if the severity of pain increases. The dose will depend on the cause of your pain and will be determined by your doctor. If you take one of these drugs for a long time and your dose goes up, your doctor may change your prescription to the extended-release form.
The most common side effects of oxycodone and hydromorphone are similar. Hydromorphone is very potent, so its side effects can be more intense. Side effects for these drugs can include:. As mentioned, the extended-release forms of these drugs can cause severe constipation, which can be dangerous. This is especially true for hydromorphone. Serotonin syndrome is a serious, life-threatening reaction that could potentially occur with Dilaudid or Percocet, especially when taken in combination with other medications that increase serotonin.
This is not a full list of side effects. Other side effects may occur. Consult your healthcare professional for a complete list of side effects of Dilaudid and Percocet. Benzodiazepines or other CNS depressants including other opioids combined with Dilaudid or Percocet can cause low blood pressure, slowed breathing, profound sedation, coma, or even death. Generally, this combination should not be used. However, if no other combination is feasible, the patient should be very closely monitored and take the combination of medications at the lowest dose s and the shortest duration possible.
Taking Dilaudid or Percocet with other medications that raise serotonin levels can increase the risk of serotonin syndrome, which is a very serious, potentially life-threatening condition. These other drugs include antidepressants, muscle relaxants, MAO inhibitors MAO inhibitors should not be used within 14 days of Dilaudid or Percocet , and triptans.
Other drug interactions may occur. Consult your healthcare provider for a full list of drug interactions of Dilaudid and Percocet.
Both Dilaudid and Percocet have boxed black box warnings, which is the strongest warning required by the FDA. Tylenol acetaminophen has been associated with liver problems, which could potentially result in the need for a liver transplant, or death. Patients should be aware of the maximum daily dose of acetaminophen ask your healthcare provider and should not use other products that contain acetaminophen.
If a skin reaction occurs, stop the drug immediately and seek emergency treatment. Acetaminophen can also cause hypersensitivity reactions, which may include swelling around the lips and face, or skin reactions. If this occurs, seek emergency treatment.
Dosing errors may occur with the liquid formulation. Household measuring devices should not be used to measure Dilaudid liquid. You should only use the measuring device that comes with the prescription and is provided by the pharmacist, or another calibrated measuring device obtained from the pharmacy.
Use caution in measuring, as incorrect measuring could lead to accidental overdose and death. Both Dilaudid tablets and liquid contain sodium metabisulfite. This is a sulfite that can rarely but potentially cause allergic reactions, including anaphylaxis and life-threatening or less severe asthmatic episodes. It is more common in patients with asthma.
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