In some cases, abusing bupropion can lead to long-term psychosis. Abusing the drug, after all, will flood the system with increased levels of norepinephrine. A sudden flood of the neurotransmitter will create a need for the body to have more in order for the user to feel good, creating a dependency on the drug that is unsustainable.
A flood of neurotransmitters can send the brain into shock, triggering physical and cognitive functions to cease. Seizures can be deadly if the user is alone and unable to be helped. It is important to note, here, that certain bupropion-based drugs can be helpful to those who have epilepsy or are at risk of seizures. Wellbutrin XL, for example, is one of them. However, when taken for epilepsy, the drug is highly regulated by the prescribing doctor and only taken in safe amounts.
Misuse or prescription dependency can result in mental and bodily harm. If you believe you or a loved one is suffering from ongoing prescription addiction, give us a call at The likelihood of a user experiencing these side effects is exponentially increased if the substance is abused :.
Bupropion is a helpful drug, but should only be used under the supervision of a doctor. Because its method of action and addiction potential are still not entirely understood, even by experts, the drug still carries some big risks. Those who decide to use the drug should stick to their prescribed dosage and only take it in pill form. Particularly for those who have addictive tendencies or are prone to drug abuse, drugs like Wellbutrin should be seen simply as a temporary prescription.
Over a long period of time, after all, the body can become dependent on the drug. People who are considering the use of bupropion to help with depression or other conditions should do so while also seeking help from a dual diagnosis treatment centers, like AspenRidge , as we are experienced in treating prescription misuse use and addiction, as well as underlying mental health issues. If someone you know is addicted to or abusing bupropion, it is important to get them help.
Oftentimes, it can be difficult to identify when someone is misusing a prescribed substance. However, by recognizing that somebody has a problem, you can help them take the first steps toward overcoming their addiction and potentially save them from facing long-term health consequences. It can be prescribed by a physician. In the form of Zyban, it can be dispensed over the counter by a pharmacist And there are a whole bunch of places that will sell it to you over the Web," Long said. Dan Cass, sent out an alert noting that his office has identified at least six deaths in the province in the past two and a half years that were at least partly caused by bupropion abuse.
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Guidelines Preference is given to commenters who use real names. Stay on topic and be concise. Stimulate debate. Newer antidepressants, such as Prozac and Zoloft, don't have that property, Welsh adds. Snorting a drug gives it quick access to the brain, but it's less direct than either injecting or smoking a substance, adds Welsh, who with a colleague detailed the case study in tomorrow's issue of The New England Journal of Medicine.
Wellbutrin, or bupropion, is sold by GlaxoSmithKline. The company also markets the drug in slow-release form as Zyban for people trying to quit smoking. Seizures are a rare but documented side effect of bupropion, especially in people who take too much of the medication or scale up their dosing too quickly, as well as those with bulimia.
The boy Welsh treated, who was taking the drug for depression, said he crushed six milligram tablets, more than twice the recommended maximum daily dose. That's a lot, but not an extreme overdose, says Welsh, which makes the seizure all the more disconcerting.
The boy had told Welsh that snorting a few pills' worth of the antidepressant gave him a "rush" but no seizures. Reported effects may include euphoria, tachycardia, agitation, hallucinations, and seizures. The nasopharynx contains a highly vascularized surface area that allows for drugs to readily enter systemic circulation. It is a common route of administration for other commonly abused drugs such as cocaine, heroin, and methamphetamine.
Lewis JC et al performed an observational study in describing 67 cases of isolated bupropion insufflation over an year period using the California Poison Control System. The mean dose was mg. The most common finding was tachycardia, with agitation and tremors also being commonly observed. Seizures typically occurred within 8 hours which is more rapid than the delayed seizures reported following oral ingestions.
The crushing of pills destroys the properties that enable a pill to be sustained-release or extended-release. All patients with bupropion exposures should have an EKG obtained.
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